Thursday, August 26, 2010

Cardiomyopathy Definition, Cardiomyopathy Types and Causes

Cardiomyopathy: Cardiomyopathy is a weakening of the heart muscle or a change in heart muscle structure. It is often associated with inadequate heart pumping or other heart function problems.

Common types of cardiomyopathy include:
Specific Cardiomyopathies:
  • Alcoholic cardiomyopathy
  • Coronary artery disease
  • Congenital heart disease
  • Nutritional diseases affecting the heart
  • Ischemic (or ischaemic) cardiomyopathy
  • Hypertensive cardiomyopathy
  • Valvular cardiomyopathy
  • Inflammatory cardiomyopathy
  • Cardiomyopathy secondary to a systemic metabolic disease
  • Myocardiodystrophy
Intrinsic Cardiomyopathies – weakness in muscle of heart that is not due to an identifiable external cause.
  • Dilated cardiomyopathy (DCM) – most common form, and one of the leading indications for heart transplantation. In DCM the heart (especially the left ventricle) is enlarged and the pumping function is diminished.
  • Hypertrophic cardiomyopathy (HCM or HOCM) – genetic disorder caused by various mutations in genes encoding sarcomeric proteins. In HCM the heart muscle is thickened, which can obstruct blood flow and prevent the heart from functioning properly.
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC) – arises from an electrical disturbance of the heart in which heart muscle is replaced by fibrous scar tissue. The right ventricle is generally most affected.
  • Restrictive cardiomyopathy (RCM) – least common cardiomyopathy. The walls of the ventricles are stiff, but may not be thickened, and resist the normal filling of the heart with blood.
  • Noncompaction Cardiomyopathy – the left ventricle wall has failed to properly grow from birth and such has a spongy appearance when viewed during an echocardiogram.

Common causes of cardiomyopathy are:
Alcoholism and Cocaine use
Amyloidosis
Chemotherapy drugs
Coronary artery disease
End-stage kidney disease
High blood pressure (hypertension)
Infections due to viruses, HIV, Lyme disease, Chagas disease
Nutritional deficiencies (such as selenium, thiamine, calcium)
Pregnancy
Systemic lupus erythematosus

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